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To be a central player in cellular overall health, NAD⁺ supports the operate more info of sirtuins—proteins that regulate growing old, mitochondrial purpose, and gene expression.

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Dehydrogenases: Enzymes in check here glycolysis and the citric acid cycle that count on NAD⁺ for redox reactions.

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Critical enzymes like NAMPT and NNMT regulate these pathways and so are central to NAD⁺ homeostasis—generating them promising therapeutic targets.

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